Clark will partner Donna Kellogg in the mixed doubles as England take on Japan.
The Ellistown ace also features in the men’s doubles, where he partners Nathan Robertson, the Olympic silver medallist.
Clark, who has worked on his game at the University over the years, is relishing the prospect of teaming up with Kellogg for the county’s first England international in more than 15 years.
He has also forged a successful partnership with Robertson, the duo having recently won Britain’s first ever World Super Series title at the Singapore Open.
"It’s a perfect scenario to be able to play an international fixture just 10 minutes from where I live," Clark said. "It’s great that all my friends and family can come and see me play.
"I’ve trained at Loughborough University for nearly 14 years now. That’s such a long time and I’ve always said I wanted to play in an international fixture here, so to be able to gain a full blown England cap is really nice.
"It’s also great for me and Donna to be able to play together in the region we both live and train in. I hope a lot of local people are able to turn out and support us."
Clark and Kellogg joined forces in 2008 and won the European mixed doubles title in 2008.
They line up with team mates Robertson, three-time national champion Elizabeth Cann and Dutch Open champion Jenny Wallwork for the five-game international against the Japanese.
Loughborough graduate Kellogg, from Derby, is England’s most-capped current woman player with 87 going into these matches.
She has seven national and two European women’s doubles titles to her name, including four national and one European titles with Olympic silver medallist Gail Emms.
She also has four mixed doubles titles – one with Simon Archer and three in a row with Clark. Kellogg teams up with Wallwork for the women’s doubles.
The event, which is supported by the East Midlands Development Agency, starts at 5.45pm tomorrow.
Tickets, which will be available on the door, are on sale online at www.theticketfactory.com, by phone on 01908 268400 or in person from the University Sports reception.